Recognition in Emergency Department of Septic Patients at Higher Risk of Death: Beware of Patients without Fever

Recognition in Emergency Department of Septic Patients at Higher Risk of Death: Beware of Patients without Fever

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Background and Objectives: Chances of surviving sepsis increase markedly upon prompt diagnosis and treatment.As most sepsis cases initially show-up in the Emergency Department Monkey Table Lamp (ED), early recognition of a septic patient has a pivotal role in sepsis management, despite the lack of precise guidelines.The aim of this study was to identify the most accurate predictors of in-hospital mortality outcome in septic patients admitted to the ED.Materials and Methods: We compared 651 patients admitted to ED for sepsis (cases) with 363 controls (non-septic patients).A Bayesian mean multivariate logistic regression model was performed in order to identify the most accurate predictors of in-hospital mortality outcomes in septic patients.

Results: Septic shock and positive qSOFA were identified as risk factors for in-hospital mortality among septic patients admitted VIT D 1000.IU to the ED.Hyperthermia was a protective factor for in-hospital mortality.Conclusions: Physicians should bear in mind that fever is not a criterium for defining sepsis; according to our results, absence of fever upon presentation might be indicative of greater severity and diagnosis of sepsis should not be delayed.